IMA Comprima Tablet Press

IMA's Comprima tablet press was originally designed for pharmaceutical production. It used a series of new designs to solve the shortcomings of traditional tablet presses. The main feature of this equipment is the use of an internal conveying system that uses centrifugal force instead of gravity to fill the powder. This minimizes the loss of powder and reduces the separation due to the "mass flow" of the conveyor. The air trapped in the mold, and in most cases increased the yield of a particular model, especially for those difficult to handle powders. In fact, the equipment provided by IMA for a pharmaceutical company in the United Kingdom recently took advantage of this feature. Experiments have shown that this model has a high utilization rate of 99.7% for low density (0.2-0.3 g/ml) spray-dried powders.

In addition, the device also uses two compression rollers and two compression cams to maintain the pre-pressure for more than a quarter of a turn of the turntable, which improves the quality of the tablets and reduces the top cracking and delamination. In many cases, this method of production also eliminates the need to process the raw materials into pellets prior to compression. The punch press is divided into two parts: the stainless steel frame as a whole and the matching die parts, the latter being determined by actual needs. This design makes it possible to quickly change the size. For example, the largest double-sided model, the Comprima 600, takes only 60 minutes to replace the compression mold, and it takes only a similar amount of time to install the new mold. The use of a two-part compression assembly and a siliceous shaft seal assures the separation of the mechanical drive section from the contact product section and avoids contamination of the powder by the lubricating oil, thus enabling the use of a Clean-in-Place (CIP) system.

In order to meet the needs of the pharmaceutical process, IMA developed a CIP automatic cleaning system for its Comprima tablet press, completely eliminating manual cleaning by the operator. There is also the option of full cleaning, which is particularly needed for manufacturers who produce hormones or cytotoxic products. The Comprima series is available in a variety of models. Among them, Comprima 150, 200, 250, and 300 have production speeds ranging from 150,000 to 300,000 tablets per hour, and the newly introduced two-sided models Comprima 500 and 600 can provide 500,000 to 600,000 tablets per hour. Tablet production speed.

IMA claims that several new presses have been installed around the world, and customers report that the cost of purchasing equipment is quickly recovered, especially when these machines are used to produce high-value products. It is said that this is because the use of this type of machine has greatly improved the production efficiency. In general, the powder utilization rate is as high as 99% or more.

In order to make the Comprima tablet press more complete, in 2000 IMA acquired the German mechanical manufacturer Kilian, which produced machines based on conventional principles and gravity-loaded fillers via adjustable fill-shoe. The Synthesis series of tablet presses represent the latest research results from Kilian. They have excellent accessibility to the processing area and are easy to clean and maintain. In addition, their stampers can be interchanged, so they can be quickly cleaned and cross-contamination of different products can be avoided.

Source: Pharmaceutical Packaging Solutions