According to the British "New Scientist" magazine website reported on September 14, British scientists used metal-containing giant molecules to successfully create bubbles similar to cells and give them some life-like characteristics. The researchers hope to induce these bubbles to evolve into completely inorganic, self-replicating entities, in order to prove the existence of life based entirely on metals (inorganics). Related research was published in the latest German edition of Applied Chemistry.
Lee Cronin of the University of Glasgow simply mixed the polyoxometallate formed by the combination of tungsten (mostly) with other metal atoms, oxygen and phosphorus in solution to make it self-assemble into a cell-like sphere , And the resulting bubbles are called inorganic chemical cells (iCHELLs). He also modified its metal oxide skeleton to give it some of the characteristics of natural cell membranes. For example, it can selectively allow chemicals of different sizes to enter and exit the cell membrane to control what chemical reactions can occur in the cell (this is A key feature of specific cells).
The Cronin team also created a separation in the bubble that mimics the internal structure of biological cells. Even better, they have begun to move towards bubble-filling devices, by combining some oxide molecules with photosensitizing dyes for photosynthesis. Cronin said that early research results show that he can make a film that, when exposed to light, can decompose water into hydrogen ions, electrons, and oxygen, which is the first step in photosynthesis. Cronin said: "There are also signs that we can excite protons across the cell membrane to create a proton gradient, which is another key stage of using solar energy. If we can effectively integrate all the steps together, we can create A self-powered cell with metabolic components similar to plants. "
Cronin has proved that as early as last year, it can make polyoxometallates mutually matrix to achieve self-replication. He is now making bubbles on a large scale and injecting them into test tube and flask arrays filled with substances of different pH. He hopes that this mixed environment will only allow the most suitable bubbles to survive. He said that in the long run, the real test is whether cells can modify their chemical properties to adapt to different environments. Cronin hinted that his latest research could prove this, and what they showed most recently was the first bubble that could evolve.
At present, the research is still in its infancy, and other synthetic biologists have reservations about it. Manuel Poca of the University of Valencia in Spain pointed out that Cronin ’s bubbles will never become a substance like life unless they can carry DNA-like substances to achieve self-replication and evolution.
If Cronin ’s research is confirmed, the possibility of extraterrestrial life will be greatly increased. Mou Zhongyuan, from the Department of Basic Sciences at the University of Tokyo in Japan, said: "There is likely to be some extraterrestrial life that is not based on carbon. For example, the material on Mercury is very different from the material on Earth. There may be organisms formed from inorganic components. Cronin is unable to prove this for the time being, but he points out a new direction. "
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